GRIN2D Antikörper (Internal Region)
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- Target Alle GRIN2D Antikörper anzeigen
- GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GRIN2D Antikörper ist unkonjugiert
- Applikation
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- GRIN2D Antibody detects endogenous levels of total GRIN2D.
- Homologie
- Pig,Bovine,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GRIN2D, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product GRIN2D Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))
- Andere Bezeichnung
- GRIN2D (GRIN2D Produkte)
- Synonyme
- nr2d antikoerper, EB11 antikoerper, GluN2D antikoerper, NMDAR2D antikoerper, NR2D antikoerper, glutamate ionotropic receptor NMDA type subunit 2D antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2D antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog antikoerper, glutamate receptor, ionotropic, NMDA2D (epsilon 4) antikoerper, GRIN2D antikoerper, grin2d.L antikoerper, grin2d antikoerper, Grin2d antikoerper
- Hintergrund
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Description: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:9489750, PubMed:27616483, PubMed:26875626, PubMed:28126851). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:9489750).
Gene: GRIN2D
- Molekulargewicht
- 170 kDa
- Gen-ID
- 2906
- UniProt
- O15399
- Pathways
- Synaptic Membrane
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