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Ube2t Antikörper (Internal Region)

Ube2t Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258234
  • Target Alle Ube2t Antikörper anzeigen
    Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 41
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 36
    • 4
    • 1
    Kaninchen
    Klonalität
    • 37
    • 4
    Polyklonal
    Konjugat
    • 20
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Ube2t Antikörper ist unkonjugiert
    Applikation
    • 30
    • 26
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    UBE2T Antibody detects endogenous levels of total UBE2T.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human UBE2T, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product Ube2t Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
    Andere Bezeichnung
    UBE2T (Ube2t Produkte)
    Synonyme
    PIG50 antikoerper, UBE2T antikoerper, 2700084L22Rik antikoerper, C80607 antikoerper, RGD1310816 antikoerper, hspc150 antikoerper, wu:fj86h11 antikoerper, zgc:153687 antikoerper, ubiquitin conjugating enzyme E2 T antikoerper, ubiquitin-conjugating enzyme E2T antikoerper, ubiquitin conjugating enzyme E2T S homeolog antikoerper, ubiquitin-conjugating enzyme E2T (putative) antikoerper, UBE2T antikoerper, Ube2t antikoerper, ube2t.S antikoerper, ube2t antikoerper
    Hintergrund

    Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair. Acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway (PubMed:16916645, PubMed:17938197, PubMed:19111657, PubMed:19589784, PubMed:28437106). Also mediates monoubiquitination of FANCL and FANCI (PubMed:16916645, PubMed:17938197, PubMed:19111657, PubMed:19589784). May contribute to ubiquitination and degradation of BRCA1 (PubMed:19887602). In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination (PubMed:20061386).

    Gene: UBE2T

    Molekulargewicht
    22 kDa
    Gen-ID
    29089
    UniProt
    Q9NPD8
    Pathways
    Chromatin Binding
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