MARK3 Antikörper (N-Term)

Produktnummer ABIN6258273

Produktdetails anti-MARK3 Antikörper

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: MARK3 Antibody detects endogenous levels of total MARK3.

Homologie: Pig,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MARK3, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MARK3

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Andere Bezeichnung: MARK3 (MARK3 Produkte)

Synonyme: MARK3 antikoerper, par1 antikoerper, par-1 antikoerper, Par-1A antikoerper, CTAK1 antikoerper, KP78 antikoerper, PAR1A antikoerper, Par-1a antikoerper, 1600015G02Rik antikoerper, A430080F22Rik antikoerper, C-TAK1 antikoerper, ETK-1 antikoerper, ETK1 antikoerper, Emk2 antikoerper, MPK10 antikoerper, fi39g08 antikoerper, wu:fi39g08 antikoerper, zgc:152848 antikoerper, zgc:55693 antikoerper, c-tak1 antikoerper, ctak1 antikoerper, emk-2 antikoerper, microtubule affinity regulating kinase 3 antikoerper, MAP/microtubule affinity-regulating kinase 3b antikoerper, MAP/microtubule affinity regulating kinase 3 antikoerper, MAP/microtubule affinity-regulating kinase 3a antikoerper, microtubule affinity regulating kinase 3 L homeolog antikoerper, MARK3 antikoerper, mark3b antikoerper, mark3 antikoerper, Mark3 antikoerper, mark3a antikoerper, mark3.L antikoerper

Hintergrund:

Description: Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613). Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714).

Gene: MARK3

Molekulargewicht: 85 kDa

Gen-ID: 4140

UniProt: P27448

Pathways: SARS-CoV-2 Protein Interaktom