PHLDA3 Antikörper (C-Term)
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- Target Alle PHLDA3 Antikörper anzeigen
- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PHLDA3 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Spezifität
- PHLDA3 Antibody detects endogenous levels of total PHLDA3.
- Homologie
- Pig,Rabbit
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PHLDA3, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product PHLDA3 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
- Andere Bezeichnung
- PHLDA3 (PHLDA3 Produkte)
- Synonyme
- TIH1 antikoerper, Tih1 antikoerper, si:dz182n13.5 antikoerper, zgc:92333 antikoerper, pleckstrin homology like domain family A member 3 antikoerper, pleckstrin homology like domain, family A, member 3 antikoerper, pleckstrin homology-like domain, family A, member 3 antikoerper, PHLDA3 antikoerper, Phlda3 antikoerper, phlda3 antikoerper
- Hintergrund
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Description: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Gene: PHLDA3
- Molekulargewicht
- 14 kDa
- Gen-ID
- 23612
- UniProt
- Q9Y5J5
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