Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SMO Antikörper (N-Term)

SMO Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258327
  • Target Alle SMO Antikörper anzeigen
    SMO (Smoothened Homolog (Drosophila) (SMO))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 57
    • 24
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 53
    • 4
    Kaninchen
    Klonalität
    • 54
    • 3
    Polyklonal
    Konjugat
    • 23
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMO Antikörper ist unkonjugiert
    Applikation
    • 44
    • 30
    • 13
    • 9
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    SMO Antibody detects endogenous levels of total SMO.
    Homologie
    Pig,Bovine,Horse,Rabbit,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human SMO, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product SMO Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    SMO (Smoothened Homolog (Drosophila) (SMO))
    Andere Bezeichnung
    SMO (SMO Produkte)
    Synonyme
    FZD11 antikoerper, Gx antikoerper, SMOH antikoerper, Smoh antikoerper, E130215L21Rik antikoerper, bnb antikoerper, smoothened antikoerper, XSmo antikoerper, smoothened, frizzled class receptor antikoerper, smoothened, frizzled class receptor L homeolog antikoerper, SMO antikoerper, Smo antikoerper, smo.L antikoerper, smo antikoerper
    Hintergrund

    Description: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7, GLI2 and GLI3 in the cilia (PubMed:19592253). Interacts with DLG5 at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation (By similarity).

    Gene: SMO

    Molekulargewicht
    86 kDa
    Gen-ID
    6608
    UniProt
    Q99835
    Pathways
    Hedgehog Signalweg
Sie sind hier:
Kundenservice