SIRT1 Antikörper (AA 577-590)
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- Target Alle SIRT1 Antikörper anzeigen
- SIRT1 (Sirtuin 1 (SIRT1))
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Bindungsspezifität
- AA 577-590
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Reaktivität
- Human
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser SIRT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Verwendungszweck
- Sirtuin 1 / SIRT1 (aa577-590)
- Sequenz
- EKPQEVQTSR NVES
- Spezifität
- This antibody is expected to recognize both reported isoforms (NP_036370.2, NP_001135970.1).
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Güteklasse
- Verified
- Immunogen
- Peptide with sequence C-EKPQEVQTSRNVES, from the internal region of the protein sequence according to NP_036370.2, NP_001135970.1.
- Isotyp
- IgG
- Top Product
- Discover our top product SIRT1 Primärantikörper
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- Applikationshinweise
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Immunohistochemistry: In paraffin embedded Human Skin shows perinuclear staining in select keratinocytes. Recommended concentration, 3-5 μg/mL.
Western Blot: Approx 120 kDa band observed in lysates of cell line Jurkat (calculated MW of 81.7 kDa according to NP_036370.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Cheng et al, Proc Natl Ac
Peptide ELISA: antibody detection limit dilution 1:64000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Minimize freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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- Target
- SIRT1 (Sirtuin 1 (SIRT1))
- Andere Bezeichnung
- SIRT1 (SIRT1 Produkte)
- Synonyme
- sirtuin 1 antikoerper, AA673258 antikoerper, SIR2L1 antikoerper, Sir2 antikoerper, Sir2a antikoerper, Sir2alpha antikoerper, sir2l1 antikoerper, sirtuin antikoerper, SIR2 antikoerper, sirtuin 1 antikoerper, sirtuin 1 L homeolog antikoerper, SIRT1 antikoerper, SRT1 antikoerper, Sirt1 antikoerper, sirt1.L antikoerper
- Hintergrund
- SIRT1, sirtuin 1, SIR2L1, NAD-dependent deacetylase sirtuin-1, OTTHUMP00000198111, OTTHUMP00000198112, SIR2-like protein 1, SIR2alpha, hSIR2, hSIRT1, sir2-like 1, sirtuin type 1
- Gen-ID
- 23411, 93759
- NCBI Accession
- NP_036370, NP_001135970
- Pathways
- MAPK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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