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CENPT Antikörper (Internal Region)

CENPT Reaktivität: Human, Maus WB, ELISA, ICC, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258439
  • Target Alle CENPT Antikörper anzeigen
    CENPT (Centromere Protein T (CENPT))
    Bindungsspezifität
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 22
    • 16
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 36
    • 1
    Kaninchen
    Klonalität
    • 37
    Polyklonal
    Konjugat
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CENPT Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Spezifität
    CENPT Antibody detects endogenous levels of total CENPT.
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CENPT, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product CENPT Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    CENPT (Centromere Protein T (CENPT))
    Andere Bezeichnung
    CENPT (CENPT Produkte)
    Synonyme
    cenp-t antikoerper, MGC145722 antikoerper, CENP-T antikoerper, wu:fc31h11 antikoerper, wu:fc75c05 antikoerper, C16orf56 antikoerper, G630055P03Rik antikoerper, RGD1309383 antikoerper, centromere protein T antikoerper, centromere protein T L homeolog antikoerper, si:ch211-225g23.1 antikoerper, cenpt antikoerper, cenpt.L antikoerper, CENPT antikoerper, si:ch211-225g23.1 antikoerper, Cenpt antikoerper
    Hintergrund

    Description: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis.

    Gene: CENPT

    Molekulargewicht
    65 kDa
    Gen-ID
    80152
    UniProt
    Q96BT3
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