Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Chp2 Antikörper (Internal Region)

Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258442
  • Target Alle Chp2 Produkte
    Chp2
    Bindungsspezifität
    • 3
    • 2
    • 1
    • 1
    Internal Region
    Reaktivität
    • 15
    • 11
    • 11
    • 1
    Human, Maus, Ratte
    Wirt
    • 13
    • 2
    Kaninchen
    Klonalität
    • 13
    • 2
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Chp2 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC)
    Spezifität
    CHP2 Antibody detects endogenous levels of total CHP2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CHP2, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    Chp2
    Abstract
    Chp2 Produkte
    Synonyme
    2010110P09Rik antikoerper, Cbhp2 antikoerper, chp-2 antikoerper, calcineurin-like EF hand protein 2 antikoerper, calcineurin like EF-hand protein 2 antikoerper, Chp2 antikoerper, CHP2 antikoerper
    Hintergrund

    Description: Functions as an integral cofactor in cell  pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing  pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.

    Gene: CHP2

    Molekulargewicht
    22 kDa
    Gen-ID
    63928
    UniProt
    O43745
Sie sind hier:
Kundenservice