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TCF7 Antikörper

TCF7 Reaktivität: Human, Maus WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258455
  • Target Alle TCF7 Antikörper anzeigen
    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
    Reaktivität
    • 55
    • 38
    • 17
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 52
    • 5
    • 1
    Kaninchen
    Klonalität
    • 51
    • 7
    Polyklonal
    Konjugat
    • 37
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser TCF7 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 16
    • 16
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    TCF7 Antibody detects endogenous levels of total TCF7
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide
    Isotyp
    IgG
    Top Product
    Discover our top product TCF7 Primärantikörper
  • Applikationshinweise
    WB 1:500~1:1000, IF/ICC 1:100-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C.Stable for 12 months from date of receipt
    Haltbarkeit
    12 months
  • Target
    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
    Andere Bezeichnung
    TCF7 (TCF7 Produkte)
    Synonyme
    TCF-1 antikoerper, AI465550 antikoerper, Tcf1 antikoerper, Xtcf-1 antikoerper, Xtcf1 antikoerper, tcf-1 antikoerper, tcf1 antikoerper, tcf7 antikoerper, transcription factor 7 antikoerper, transcription factor 7, T cell specific antikoerper, transcription factor 7 S homeolog antikoerper, TCF7 antikoerper, Tcf7 antikoerper, tcf7 antikoerper, tcf7.S antikoerper
    Hintergrund

    Description: Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ CD8+ immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.

    Gene: TCF7

    Molekulargewicht
    42 kDa
    Gen-ID
    6932
    UniProt
    P36402
    Pathways
    WNT Signalweg
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