TCF7 Antikörper
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- Target Alle TCF7 Antikörper anzeigen
- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TCF7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- TCF7 Antibody detects endogenous levels of total TCF7
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide
- Isotyp
- IgG
- Top Product
- Discover our top product TCF7 Primärantikörper
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- Applikationshinweise
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
- Andere Bezeichnung
- TCF7 (TCF7 Produkte)
- Synonyme
- TCF-1 antikoerper, AI465550 antikoerper, Tcf1 antikoerper, Xtcf-1 antikoerper, Xtcf1 antikoerper, tcf-1 antikoerper, tcf1 antikoerper, tcf7 antikoerper, transcription factor 7 antikoerper, transcription factor 7, T cell specific antikoerper, transcription factor 7 S homeolog antikoerper, TCF7 antikoerper, Tcf7 antikoerper, tcf7 antikoerper, tcf7.S antikoerper
- Hintergrund
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Description: Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ CD8+ immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
Gene: TCF7
- Molekulargewicht
- 42 kDa
- Gen-ID
- 6932
- UniProt
- P36402
- Pathways
- WNT Signalweg
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