RNF144B Antikörper (Internal Region)
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- Target Alle RNF144B Antikörper anzeigen
- RNF144B (Ring Finger Protein 144B (RNF144B))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RNF144B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- RNF144B Antibody detects endogenous levels of total RNF144B.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RNF144B, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product RNF144B Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- RNF144B (Ring Finger Protein 144B (RNF144B))
- Andere Bezeichnung
- RNF144B (RNF144B Produkte)
- Synonyme
- IBRDC2 antikoerper, PIR2 antikoerper, bA528A10.3 antikoerper, p53RFP antikoerper, BC025007 antikoerper, E130105P19Rik antikoerper, Ibrdc2 antikoerper, Pir2 antikoerper, ring finger protein 144B antikoerper, RNF144B antikoerper, Rnf144b antikoerper
- Hintergrund
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Description: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death, But, it is not an anti-apoptotic protein per se.
Gene: RNF144B
- Molekulargewicht
- 33 kDa
- Gen-ID
- 255488
- UniProt
- Q7Z419
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