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TSEN54 Antikörper (Internal Region)

TSEN54 Reaktivität: Human, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258653
  • Target Alle TSEN54 Antikörper anzeigen
    TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))
    Bindungsspezifität
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 13
    • 8
    • 1
    Human, Maus
    Wirt
    • 12
    • 1
    Kaninchen
    Klonalität
    • 13
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TSEN54 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    TSEN54 Antibody detects endogenous levels of total TSEN54.
    Homologie
    Bovine
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TSEN54, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))
    Andere Bezeichnung
    TSEN54 (TSEN54 Produkte)
    Synonyme
    zgc:109927 antikoerper, 0610034P02Rik antikoerper, PCH2A antikoerper, PCH4 antikoerper, SEN54L antikoerper, sen54 antikoerper, tRNA splicing endonuclease subunit 54 antikoerper, TSEN54 tRNA splicing endonuclease subunit antikoerper, tRNA splicing endonuclease 54 homolog (S. cerevisiae) antikoerper, TSEN54 antikoerper, tsen54 antikoerper, Tsen54 antikoerper
    Hintergrund

    Description: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.

    Gene: TSEN54

    Molekulargewicht
    59 kDa
    Gen-ID
    283989
    UniProt
    Q7Z6J9
    Pathways
    Synaptic Membrane
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