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FZD10 Antikörper

FZD10 Reaktivität: Human, Maus, Affe WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258746
  • Target Alle FZD10 Antikörper anzeigen
    FZD10 (Frizzled Family Receptor 10 (FZD10))
    Reaktivität
    • 43
    • 39
    • 19
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    Human, Maus, Affe
    Wirt
    • 47
    Kaninchen
    Klonalität
    • 46
    • 1
    Polyklonal
    Konjugat
    • 19
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FZD10 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 13
    • 13
    • 13
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    FZD10 antibody detects endogenous levels of total FZD10
    Kreuzreaktivität
    Human, Affe, Maus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide
    Isotyp
    IgG
    Top Product
    Discover our top product FZD10 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IF/ICC 1:100-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    FZD10 (Frizzled Family Receptor 10 (FZD10))
    Andere Bezeichnung
    FZD10 (FZD10 Produkte)
    Hintergrund

    Description: Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).

    Gene: FZD10

    Molekulargewicht
    65 kDa
    Gen-ID
    11211
    UniProt
    Q9ULW2
    Pathways
    WNT Signalweg
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