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CDK5R1 Antikörper (N-Term)

CDK5R1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258750
  • Target Alle CDK5R1 Antikörper anzeigen
    CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
    Bindungsspezifität
    • 16
    • 10
    • 9
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 54
    • 47
    • 20
    • 12
    • 11
    • 10
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 51
    • 17
    • 1
    Kaninchen
    Klonalität
    • 45
    • 24
    Polyklonal
    Konjugat
    • 24
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CDK5R1 Antikörper ist unkonjugiert
    Applikation
    • 54
    • 37
    • 33
    • 16
    • 14
    • 13
    • 13
    • 10
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    CDK5R1/P35 Antibody detects endogenous levels of total CDK5R1/P35.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CDK5R1/P35, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product CDK5R1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
    Andere Bezeichnung
    CDK5R1 (CDK5R1 Produkte)
    Synonyme
    CDK5P35 antikoerper, CDK5R antikoerper, NCK5A antikoerper, p23 antikoerper, p25 antikoerper, p35 antikoerper, p35nck5a antikoerper, cdk5r1 antikoerper, zgc:92814 antikoerper, CDK5R1 antikoerper, Cdk5r antikoerper, P25/P35 antikoerper, D11Bwg0379e antikoerper, Xp35.1 antikoerper, cyclin dependent kinase 5 regulatory subunit 1 antikoerper, cyclin-dependent kinase 5, regulatory subunit 1b (p35) antikoerper, cyclin-dependent kinase 5 regulatory subunit 1 antikoerper, S100 calcium binding protein A9 antikoerper, cyclin-dependent kinase 5, regulatory subunit 1 (p35) antikoerper, cyclin-dependent kinase 5, regulatory subunit 1 (p35) L homeolog antikoerper, CDK5R1 antikoerper, cdk5r1b antikoerper, Cdk5r1 antikoerper, S100A9 antikoerper, cdk5r1.L antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund

    Description: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.

    Gene: CDK5R1

    Molekulargewicht
    38 kDa
    Gen-ID
    8851
    UniProt
    Q15078
    Pathways
    Stem Cell Maintenance, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
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