LFNG Antikörper (Internal Region)

Produktnummer ABIN6258872

Produktdetails anti-LFNG Antikörper

Target: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LFNG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: LFNG Antibody detects endogenous levels of total LFNG.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human LFNG, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu LFNG

Target: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Andere Bezeichnung: LFNG (LFNG Produkte)

Synonyme: SCDO3 antikoerper, AW061165 antikoerper, id:ibd2614 antikoerper, id:ibd5029 antikoerper, id:ibd5138 antikoerper, l-fng antikoerper, wu:fc69h02 antikoerper, wu:fi34c01 antikoerper, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antikoerper, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase S homeolog antikoerper, LFNG antikoerper, Lfng antikoerper, lfng.S antikoerper, lfng antikoerper

Hintergrund:

Description: Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity). Decreases the binding of JAG1 to NOTCH2 but not that of DLL1 (PubMed:11346656). Essential mediator of somite segmentation and patterning (By similarity).

Gene: LFNG

Molekulargewicht: 42 kDa

Gen-ID: 3955

UniProt: Q8NES3

Pathways: Notch Signalweg