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GNL3L Antikörper

GNL3L Reaktivität: Human ELISA, WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258968
  • Target Alle GNL3L Antikörper anzeigen
    GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
    Reaktivität
    • 33
    • 18
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 48
    Kaninchen
    Klonalität
    • 48
    Polyklonal
    Konjugat
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GNL3L Antikörper ist unkonjugiert
    Applikation
    • 23
    • 22
    • 14
    • 13
    • 13
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    GNL3L Antibody detects endogenous levels of total GNL3L
    Kreuzreaktivität
    Human
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide
    Isotyp
    IgG
    Top Product
    Discover our top product GNL3L Primärantikörper
  • Applikationshinweise
    WB 1:500~1:1000, IF/ICC 1:100-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C.Stable for 12 months from date of receipt
    Haltbarkeit
    12 months
  • Target
    GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
    Andere Bezeichnung
    GNL3L (GNL3L Produkte)
    Synonyme
    SI:zK13A21.8 antikoerper, flj10613 antikoerper, flj10613l antikoerper, si:dkey-13a21.8 antikoerper, zgc:110536 antikoerper, BC020354 antikoerper, guanine nucleotide binding protein-like 3 (nucleolar)-like antikoerper, guanine nucleotide binding protein-like 3 (nucleolar)-like S homeolog antikoerper, G protein nucleolar 3 like antikoerper, gnl3l antikoerper, gnl3l.S antikoerper, GNL3L antikoerper, Gnl3l antikoerper
    Hintergrund

    Description: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.

    Gene: GNL3L

    Molekulargewicht
    66 kDa
    Gen-ID
    54552
    UniProt
    Q9NVN8
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