GNL3L Antikörper
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- Target Alle GNL3L Antikörper anzeigen
- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GNL3L Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- GNL3L Antibody detects endogenous levels of total GNL3L
- Kreuzreaktivität
- Human
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide
- Isotyp
- IgG
- Top Product
- Discover our top product GNL3L Primärantikörper
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- Applikationshinweise
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
- Andere Bezeichnung
- GNL3L (GNL3L Produkte)
- Synonyme
- SI:zK13A21.8 antikoerper, flj10613 antikoerper, flj10613l antikoerper, si:dkey-13a21.8 antikoerper, zgc:110536 antikoerper, BC020354 antikoerper, guanine nucleotide binding protein-like 3 (nucleolar)-like antikoerper, guanine nucleotide binding protein-like 3 (nucleolar)-like S homeolog antikoerper, G protein nucleolar 3 like antikoerper, gnl3l antikoerper, gnl3l.S antikoerper, GNL3L antikoerper, Gnl3l antikoerper
- Hintergrund
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Description: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
Gene: GNL3L
- Molekulargewicht
- 66 kDa
- Gen-ID
- 54552
- UniProt
- Q9NVN8
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