PARP2 Antikörper (Internal Region)
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- Target Alle PARP2 Antikörper anzeigen
- PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PARP2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- PARP2 Antibody detects endogenous levels of total PARP2.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PARP2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
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anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) (Internal Region) antibody
Verified PARP2 Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) (AA 401-450) antibodyPARP2 Reaktivität: Human, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) (Middle Region) antibodyPARP2 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) (AA 14-149) antibodyPARP2 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) (Internal Region) antibodyPARP2 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) (AA 10-40), (N-Term) antibodyPARP2 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB15192 unconjugated
anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) (AA 306-336), (C-Term) antibodyPARP2 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB14156 unconjugated
anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) antibodyPARP2 Reaktivität: Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) (AA 450-550) antibodyPARP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 2 (PARP2) (Internal Region) antibodyPARP2 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
- Andere Bezeichnung
- PARP2 (PARP2 Produkte)
- Hintergrund
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Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism (PubMed:10364231, PubMed:28190768). This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (PubMed:10364231). Mediates serine ADP-ribosylation of target proteins following interaction with HPF1, HPF1 conferring serine specificity (PubMed:28190768).
Gene: PARP2
- Molekulargewicht
- 75 kDa
- Gen-ID
- 10038
- UniProt
- Q9UGN5
- Pathways
- DNA Reparatur
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