MSH3 Antikörper (N-Term)
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- Target Alle MSH3 Antikörper anzeigen
- MSH3 (MutS Homolog 3 (MSH3))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MSH3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- MSH3 Antibody detects endogenous levels of total MSH3.
- Homologie
- Pig,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MSH3, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
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anti-MutS Homolog 3 (MSH3) (N-Term) antibody
MSH3 Reaktivität: Human, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 136-349) antibodyMSH3 Reaktivität: Human WB, IF Wirt: Maus Monoclonal 52-MSH3 unconjugated
anti-MutS Homolog 3 (MSH3) (N-Term) antibodyMSH3 Reaktivität: Human WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (N-Term) antibodyMSH3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 651-750) antibodyMSH3 Reaktivität: Human ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 521-620) antibodyMSH3 Reaktivität: Human, Maus, Ratte WB, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (N-Term) antibodyMSH3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 617-761) antibodyMSH3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 3 (MSH3) (AA 51-100) antibodyMSH3 Reaktivität: Human WB, ELISA, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- MSH3 (MutS Homolog 3 (MSH3))
- Andere Bezeichnung
- MSH3 (MSH3 Produkte)
- Synonyme
- ATMSH3 antikoerper, M7J2.90 antikoerper, M7J2_90 antikoerper, homolog of DNA mismatch repair protein MSH3 antikoerper, DUP antikoerper, MRP1 antikoerper, D13Em1 antikoerper, Rep-3 antikoerper, Rep3 antikoerper, mutS homolog 3 antikoerper, DNA mismatch repair protein MSH3 antikoerper, homolog of DNA mismatch repair protein MSH3 antikoerper, mismatch repair protein antikoerper, MSH3 antikoerper, Msh3 antikoerper
- Hintergrund
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Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
Gene: MSH3
- Molekulargewicht
- 127 kDa
- Gen-ID
- 4437
- UniProt
- P20585
- Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
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