EPH Receptor B4 Antikörper (C-Term)

Produktnummer ABIN6259079

Produktdetails anti-EPH Receptor B4 Antikörper

Target: EPH Receptor B4 (EPHB4)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: EPHB4 Antibody detects endogenous levels of total EPHB4.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human EPHB4, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Andere Bezeichnung: EPHB4 (EPHB4 Produkte)

Synonyme: HTK antikoerper, MYK1 antikoerper, TYRO11 antikoerper, htk antikoerper, myk1 antikoerper, ephB4a antikoerper, tyro11 antikoerper, ephb4b antikoerper, MGC130997 antikoerper, AI042935 antikoerper, Htk antikoerper, MDK2 antikoerper, Myk1 antikoerper, Tyro11 antikoerper, cb646 antikoerper, ephB4 antikoerper, rtk5 antikoerper, EphB-rtk8 antikoerper, cb417 antikoerper, rtk8 antikoerper, EPH receptor B4 antikoerper, EPH receptor B4 L homeolog antikoerper, EPH receptor B4 S homeolog antikoerper, Eph receptor B4 antikoerper, eph receptor B4a antikoerper, eph receptor B4b antikoerper, EPHB4 antikoerper, ephb4.L antikoerper, ephb4.S antikoerper, ephb4 antikoerper, Ephb4 antikoerper, ephb4a antikoerper, ephb4b antikoerper

Hintergrund:

Description: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.

Gene: EPHB4

Molekulargewicht: 108 kDa

Gen-ID: 2050

UniProt: P54760

Pathways: RTK Signalweg