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MRGPRX1 Antikörper (C-Term)

MRGPRX1 Reaktivität: Human WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6259084
  • Target Alle MRGPRX1 Antikörper anzeigen
    MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
    Bindungsspezifität
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 15
    • 8
    • 4
    • 1
    Human
    Wirt
    • 23
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MRGPRX1 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    MRGX1 Antibody detects endogenous levels of total MRGX1.
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MRGX1, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product MRGPRX1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
    Andere Bezeichnung
    MRGPRX1 (MRGPRX1 Produkte)
    Synonyme
    GPCR antikoerper, MRGX1 antikoerper, SNSR4 antikoerper, MrgC11 antikoerper, Mrgprc11 antikoerper, Snsr1 antikoerper, MAS related GPR family member X1 antikoerper, MAS-related GPR, member X1 antikoerper, MRGPRX1 antikoerper, Mrgprx1 antikoerper
    Hintergrund

    Description: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.

    Gene: MRGPRX1

    Molekulargewicht
    36 kDa
    Gen-ID
    259249
    UniProt
    Q96LB2
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