MRGPRX1 Antikörper (C-Term)
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- Target Alle MRGPRX1 Antikörper anzeigen
- MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MRGPRX1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- MRGX1 Antibody detects endogenous levels of total MRGX1.
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MRGX1, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product MRGPRX1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))
- Andere Bezeichnung
- MRGPRX1 (MRGPRX1 Produkte)
- Synonyme
- GPCR antikoerper, MRGX1 antikoerper, SNSR4 antikoerper, MrgC11 antikoerper, Mrgprc11 antikoerper, Snsr1 antikoerper, MAS related GPR family member X1 antikoerper, MAS-related GPR, member X1 antikoerper, MRGPRX1 antikoerper, Mrgprx1 antikoerper
- Hintergrund
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Description: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.
Gene: MRGPRX1
- Molekulargewicht
- 36 kDa
- Gen-ID
- 259249
- UniProt
- Q96LB2
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