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MASTL Antikörper (C-Term)

MASTL Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6259099
  • Target Alle MASTL Antikörper anzeigen
    MASTL (Microtubule Associated serine/threonine Kinase-Like (MASTL))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 45
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 45
    • 14
    Kaninchen
    Klonalität
    • 44
    • 15
    Polyklonal
    Konjugat
    • 25
    • 7
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MASTL Antikörper ist unkonjugiert
    Applikation
    • 45
    • 37
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    MASTL Antibody detects endogenous levels of total MASTL.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MASTL, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product MASTL Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    MASTL (Microtubule Associated serine/threonine Kinase-Like (MASTL))
    Andere Bezeichnung
    MASTL (MASTL Produkte)
    Synonyme
    GW antikoerper, GWL antikoerper, MAST-L antikoerper, im:7149025 antikoerper, wu:fa02a12 antikoerper, zgc:100990 antikoerper, MASTL antikoerper, GREATWALL antikoerper, RP11-85G18.2 antikoerper, THC2 antikoerper, hGWL antikoerper, 2700091H24Rik antikoerper, C88295 antikoerper, greatwall antikoerper, thc2 antikoerper, microtubule associated serine/threonine kinase-like antikoerper, microtubule associated serine/threonine kinase like antikoerper, serine/threonine-protein kinase greatwall antikoerper, microtubule associated serine/threonine kinase like L homeolog antikoerper, mastl antikoerper, MASTL antikoerper, LOC100541707 antikoerper, Mastl antikoerper, mastl.L antikoerper
    Hintergrund

    Description: Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro, however such activity is unsure in vivo. May be involved in megakaryocyte differentiation.

    Gene: MASTL

    Molekulargewicht
    97 kDa
    Gen-ID
    84930
    UniProt
    Q96GX5
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