NK2 Homeobox 5 Antikörper (Internal Region)

Produktnummer ABIN6259127

Produktdetails anti-NK2 Homeobox 5 Antikörper

Target: NK2 Homeobox 5 (NKX2-5)

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NK2 Homeobox 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Nkx2.5 Antibody detects endogenous levels of total Nkx2.5.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Nkx2.5, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu NK2 Homeobox 5

Target: NK2 Homeobox 5 (NKX2-5)

Andere Bezeichnung: NKX2-5 (NKX2-5 Produkte)

Synonyme: CHNG5 antikoerper, CSX antikoerper, CSX1 antikoerper, HLHS2 antikoerper, NKX2.5 antikoerper, NKX2E antikoerper, NKX4-1 antikoerper, VSD3 antikoerper, Csx antikoerper, Nkx-2.5 antikoerper, Nkx2.5 antikoerper, tinman antikoerper, nk2.5 antikoerper, nkx2-5 antikoerper, zgc:111912 antikoerper, AR2 antikoerper, XNkx2-5 antikoerper, csx antikoerper, nkx-2.5 antikoerper, nkx2-5b antikoerper, nkx2.5 antikoerper, NKX2-5 antikoerper, Nkx2-5 antikoerper, csx1 antikoerper, nkx2e antikoerper, XNkx-2.5 antikoerper, CNKX-2.5 antikoerper, NKX-2.5 antikoerper, NK2 homeobox 5 antikoerper, NK2 homeobox 5 S homeolog antikoerper, NKX2-5 antikoerper, Nkx2-5 antikoerper, nkx2.5 antikoerper, nkx2-5.S antikoerper, nkx2-5 antikoerper

Hintergrund:

Description: Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). Binds to the core DNA motif of NPPA promoter (PubMed:22849347, PubMed:26926761). It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development.

Gene: NKX2-5

Molekulargewicht: 50 kDa

Gen-ID: 1482

UniProt: P52952

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development