PAX4 Antikörper (Internal Region)
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- Target Alle PAX4 Antikörper anzeigen
- PAX4 (Paired Box 4 (PAX4))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PAX4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- PAX4 Antibody detects endogenous levels of total PAX4.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PAX4, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product PAX4 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- PAX4 (Paired Box 4 (PAX4))
- Andere Bezeichnung
- PAX4 (PAX4 Produkte)
- Synonyme
- KPD antikoerper, MODY9 antikoerper, Pax-4 antikoerper, PAX4 antikoerper, paired box 4 antikoerper, PAX4 antikoerper, Pax4 antikoerper
- Hintergrund
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Description: Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.
Gene: PAX4
- Molekulargewicht
- 42 kDa
- Gen-ID
- 5078
- UniProt
- O43316
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