RRAGB Antikörper (Internal Region)
-
- Target Alle RRAGB Antikörper anzeigen
- RRAGB (Ras-Related GTP Binding B (RRAGB))
-
Bindungsspezifität
- Internal Region
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser RRAGB Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Spezifität
- RRAGB Antibody detects endogenous levels of total RRAGB.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RRAGB, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product RRAGB Primärantikörper
-
-
- Applikationshinweise
- WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
-
- Target
- RRAGB (Ras-Related GTP Binding B (RRAGB))
- Andere Bezeichnung
- RRAGB (RRAGB Produkte)
- Synonyme
- RAGB antikoerper, bA465E19.1 antikoerper, Ragb antikoerper, RRAGB antikoerper, Ras related GTP binding B antikoerper, Ras-related GTP binding B antikoerper, RRAGB antikoerper, RragB antikoerper, Rragb antikoerper
- Hintergrund
-
Description: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
Gene: RRAGB
- Molekulargewicht
- 43 kDa
- Gen-ID
- 10325
- UniProt
- Q5VZM2
-