PPHLN1 Antikörper (N-Term)
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- Target Alle PPHLN1 Antikörper anzeigen
- PPHLN1 (Periphilin 1 (PPHLN1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PPHLN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- PPHLN Antibody detects endogenous levels of total PPHLN.
- Homologie
- Pig,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PPHLN, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product PPHLN1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- PPHLN1 (Periphilin 1 (PPHLN1))
- Andere Bezeichnung
- PPHLN1 (PPHLN1 Produkte)
- Synonyme
- MGC75908 antikoerper, MGC81987 antikoerper, wu:fb83c09 antikoerper, zgc:158246 antikoerper, si:ch211-155a11.2 antikoerper, HSPC232 antikoerper, 1110063K05Rik antikoerper, 1600022A19Rik antikoerper, CR antikoerper, HSPC206 antikoerper, periphilin 1 antikoerper, periphilin 1 S homeolog antikoerper, PPHLN1 antikoerper, pphln1 antikoerper, pphln1.S antikoerper, Pphln1 antikoerper
- Hintergrund
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Description: Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. In the HUSH complex, contributes to the maintenance of the complex at chromatin (PubMed:26022416). Acts as a transcriptional corepressor and regulates the cell cycle, probably via the HUSH complex (PubMed:15474462, PubMed:17963697). May be involved in epithelial differentiation by contributing to epidermal integrity and barrier formation (Probable).
Gene: PPHLN1
- Molekulargewicht
- 53 kDa
- Gen-ID
- 51535
- UniProt
- Q8NEY8
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