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PPHLN1 Antikörper (N-Term)

PPHLN1 Reaktivität: Human, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6259270
  • Target Alle PPHLN1 Antikörper anzeigen
    PPHLN1 (Periphilin 1 (PPHLN1))
    Bindungsspezifität
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 34
    • 21
    • 16
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 32
    • 3
    Kaninchen
    Klonalität
    • 33
    • 2
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PPHLN1 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 13
    • 13
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    PPHLN Antibody detects endogenous levels of total PPHLN.
    Homologie
    Pig,Sheep,Rabbit,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human PPHLN, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product PPHLN1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    PPHLN1 (Periphilin 1 (PPHLN1))
    Andere Bezeichnung
    PPHLN1 (PPHLN1 Produkte)
    Synonyme
    MGC75908 antikoerper, MGC81987 antikoerper, wu:fb83c09 antikoerper, zgc:158246 antikoerper, si:ch211-155a11.2 antikoerper, HSPC232 antikoerper, 1110063K05Rik antikoerper, 1600022A19Rik antikoerper, CR antikoerper, HSPC206 antikoerper, periphilin 1 antikoerper, periphilin 1 S homeolog antikoerper, PPHLN1 antikoerper, pphln1 antikoerper, pphln1.S antikoerper, Pphln1 antikoerper
    Hintergrund

    Description: Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. In the HUSH complex, contributes to the maintenance of the complex at chromatin (PubMed:26022416). Acts as a transcriptional corepressor and regulates the cell cycle, probably via the HUSH complex (PubMed:15474462, PubMed:17963697). May be involved in epithelial differentiation by contributing to epidermal integrity and barrier formation (Probable).

    Gene: PPHLN1

    Molekulargewicht
    53 kDa
    Gen-ID
    51535
    UniProt
    Q8NEY8
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