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STK36 Antikörper (Internal Region)

STK36 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6259306
  • Target Alle STK36 Antikörper anzeigen
    STK36 (serine/threonine Kinase 36 (STK36))
    Bindungsspezifität
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 16
    • 2
    • 1
    Kaninchen
    Klonalität
    • 19
    Polyklonal
    Konjugat
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STK36 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    STK36 Antibody detects endogenous levels of total STK36.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human STK36, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product STK36 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    STK36 (serine/threonine Kinase 36 (STK36))
    Andere Bezeichnung
    STK36 (STK36 Produkte)
    Synonyme
    FU antikoerper, fused-like antikoerper, 1700112N14Rik antikoerper, B930045J24 antikoerper, Fused antikoerper, mKIAA1278 antikoerper, fu antikoerper, si:dkey-180i4.3 antikoerper, zgc:152944 antikoerper, serine/threonine kinase 36 antikoerper, serine/threonine kinase 36 (fused homolog, Drosophila) antikoerper, STK36 antikoerper, Stk36 antikoerper, stk36 antikoerper
    Hintergrund

    Description: Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors (PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization (PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur (PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function (By similarity). Essential for construction of the central pair apparatus of motile cilia.

    Gene: STK36

    Molekulargewicht
    170 kDa
    Gen-ID
    27148
    UniProt
    Q9NRP7
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