ALKBH4 Antikörper (Internal Region)

Produktnummer ABIN6259501

Produktdetails anti-ALKBH4 Antikörper

Target: ALKBH4 (AlkB, Alkylation Repair Homolog 4 (E. Coli) (ALKBH4))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALKBH4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: ALKBH4 Antibody detects endogenous levels of total ALKBH4.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ALKBH4, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu ALKBH4

Target: ALKBH4 (AlkB, Alkylation Repair Homolog 4 (E. Coli) (ALKBH4))

Andere Bezeichnung: ALKBH4 (ALKBH4 Produkte)

Synonyme: ABH4 antikoerper, 2010004B12Rik antikoerper, Abj4 antikoerper, alkB homolog 4, lysine demethylase antikoerper, ALKBH4 antikoerper, Alkbh4 antikoerper

Hintergrund:

Description: Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.

Gene: ALKBH4

Molekulargewicht: 36 kDa

Gen-ID: 54784

UniProt: Q9NXW9