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WEE2 Antikörper

WEE2 Reaktivität: Human, Maus WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6259536
  • Target Alle WEE2 Antikörper anzeigen
    WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
    Reaktivität
    Human, Maus
    Wirt
    • 25
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser WEE2 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    WEE2 Antibody detects endogenous levels of total WEE2
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500~1:1000, IF/ICC 1:100-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C.Stable for 12 months from date of receipt
    Haltbarkeit
    12 months
  • Target
    WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
    Andere Bezeichnung
    WEE2 (WEE2 Produkte)
    Synonyme
    Xe-wee1 antikoerper, wee1 antikoerper, wee1-b antikoerper, wee1a antikoerper, wee1b antikoerper, wee2-b antikoerper, xwee1 antikoerper, xwee2 antikoerper, WEE1B antikoerper, Gm1065 antikoerper, Wee1B antikoerper, WEE2 antikoerper, im:5913035 antikoerper, si:ch211-238n5.5 antikoerper, wu:fi13b10 antikoerper, zgc:123074 antikoerper, WEE1 homolog 2 antikoerper, WEE1 homolog 2 (S. pombe) antikoerper, wee2 antikoerper, WEE2 antikoerper, Wee2 antikoerper
    Hintergrund

    Description: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).

    Gene: WEE2

    Molekulargewicht
    60 kDa
    Gen-ID
    494551
    UniProt
    P0C1S8
    Pathways
    M Phase
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