ZAK Antikörper (N-Term)

Produktnummer ABIN6259601

Produktdetails anti-ZAK Antikörper

Target: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZAK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: ZAK Antibody detects endogenous levels of total ZAK.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZAK, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ZAK

Target: ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

Andere Bezeichnung: MAP3K20 (ZAK Produkte)

Synonyme: MLTK antikoerper, RGD1561394 antikoerper, AZK antikoerper, MLK7 antikoerper, MLT antikoerper, MRK antikoerper, mlklak antikoerper, pk antikoerper, AV006891 antikoerper, B230120H23Rik antikoerper, MLTKalpha antikoerper, MLTKbeta antikoerper, mitogen-activated protein kinase kinase kinase 20 antikoerper, Map3k20 antikoerper, MAP3K20 antikoerper

Hintergrund:

Description: Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2 (PubMed:10924358, PubMed:11836244, PubMed:15342622, PubMed:21224381). Involved in limb development (PubMed:26755636).

Gene: MAP3K20

Molekulargewicht: 91 kDa

Gen-ID: 51776

UniProt: Q9NYL2