ADRM1 Antikörper (Internal Region)

Produktnummer ABIN6259812

Produktdetails anti-ADRM1 Antikörper

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: ADRM1 Antibody detects endogenous levels of total ADRM1.

Homologie: Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ADRM1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ADRM1

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Andere Bezeichnung: ADRM1 (Adrm1 Produkte)

Synonyme: arm-1 antikoerper, gp110 antikoerper, rpn13 antikoerper, xoom antikoerper, ADRM1 antikoerper, adrm1 antikoerper, ARM-1 antikoerper, ARM1 antikoerper, GP110 antikoerper, 1110063P18Rik antikoerper, 2510006J17Rik antikoerper, AA408205 antikoerper, AU043535 antikoerper, Arm1 antikoerper, Gp110 antikoerper, Rpn13 antikoerper, adrm1a antikoerper, adrm1b antikoerper, fa12d09 antikoerper, wu:fa10g10 antikoerper, wu:fa12d09 antikoerper, zgc:56107 antikoerper, zgc:77256 antikoerper, adhesion regulating molecule 1 antikoerper, ADRM1 antikoerper, 19S proteasome regulatory subunit antikoerper, ADRM1 protein antikoerper, adrm1 antikoerper, ADRM1 antikoerper, CpipJ_CPIJ002929 antikoerper, SJAG_04211 antikoerper, Adrm1 antikoerper

Hintergrund:

Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.

Gene: ADRM1

Molekulargewicht: 46 kDa

Gen-ID: 11047

UniProt: Q16186

Pathways: Positive Regulation of Endopeptidase Activity