AFG3L2 Antikörper (C-Term)
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- Target Alle AFG3L2 Antikörper anzeigen
- AFG3L2 (AFG3-Like Protein 2 (AFG3L2))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AFG3L2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- AFG3L2 Antibody detects endogenous levels of total AFG3L2.
- Homologie
- Pig,Bovine,Sheep,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human AFG3L2, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product AFG3L2 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- AFG3L2 (AFG3-Like Protein 2 (AFG3L2))
- Andere Bezeichnung
- AFG3L2 (AFG3L2 Produkte)
- Synonyme
- MGC147390 antikoerper, si:ch211-12e1.4 antikoerper, SCA28 antikoerper, SPAX5 antikoerper, 2310036I02Rik antikoerper, AW260507 antikoerper, Emv66 antikoerper, par antikoerper, AFG3 like matrix AAA peptidase subunit 2 antikoerper, AFG3-like protein 2 antikoerper, AFG3 ATPase family gene 3-like 2 (S. cerevisiae) antikoerper, AFG3-like AAA ATPase 2 antikoerper, AFG3-like AAA ATPase 2 L homeolog antikoerper, AFG3L2 antikoerper, LOC578526 antikoerper, afg3l2 antikoerper, afg3l2.L antikoerper, Afg3l2 antikoerper
- Hintergrund
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Description: ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).
Gene: AFG3L2
- Molekulargewicht
- 80-90 kDa
- Gen-ID
- 10939
- UniProt
- Q9Y4W6
- Pathways
- Skeletal Muscle Fiber Development
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