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AFG3L2 Antikörper (C-Term)

AFG3L2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6259816
  • Target Alle AFG3L2 Antikörper anzeigen
    AFG3L2 (AFG3-Like Protein 2 (AFG3L2))
    Bindungsspezifität
    • 8
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 43
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 41
    • 3
    Kaninchen
    Klonalität
    • 43
    • 1
    Polyklonal
    Konjugat
    • 19
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AFG3L2 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 25
    • 23
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    AFG3L2 Antibody detects endogenous levels of total AFG3L2.
    Homologie
    Pig,Bovine,Sheep,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human AFG3L2, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
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    Discover our top product AFG3L2 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    AFG3L2 (AFG3-Like Protein 2 (AFG3L2))
    Andere Bezeichnung
    AFG3L2 (AFG3L2 Produkte)
    Synonyme
    MGC147390 antikoerper, si:ch211-12e1.4 antikoerper, SCA28 antikoerper, SPAX5 antikoerper, 2310036I02Rik antikoerper, AW260507 antikoerper, Emv66 antikoerper, par antikoerper, AFG3 like matrix AAA peptidase subunit 2 antikoerper, AFG3-like protein 2 antikoerper, AFG3 ATPase family gene 3-like 2 (S. cerevisiae) antikoerper, AFG3-like AAA ATPase 2 antikoerper, AFG3-like AAA ATPase 2 L homeolog antikoerper, AFG3L2 antikoerper, LOC578526 antikoerper, afg3l2 antikoerper, afg3l2.L antikoerper, Afg3l2 antikoerper
    Hintergrund

    Description: ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).

    Gene: AFG3L2

    Molekulargewicht
    80-90 kDa
    Gen-ID
    10939
    UniProt
    Q9Y4W6
    Pathways
    Skeletal Muscle Fiber Development
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