AGO1 Antikörper (Internal Region)

Produktnummer ABIN6259824

Produktdetails anti-AGO1 Antikörper

Target: AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: AGO1 Antibody detects endogenous levels of total AGO1.

Homologie: Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AGO1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu AGO1

Target: AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))

Andere Bezeichnung: AGO1 (EIF2C1 Produkte)

Synonyme: Ago antikoerper, Ago-1 antikoerper, Ago1 antikoerper, CG6671 antikoerper, Dm Ago1 antikoerper, Dmel\\CG6671 antikoerper, MRE20 antikoerper, ago1 antikoerper, ago1-1 antikoerper, anon-WO0257455.29 antikoerper, dAGO1 antikoerper, dAgo1 antikoerper, l(2)04845 antikoerper, l(2)4845 antikoerper, l(2)k00208 antikoerper, l(2)k08121 antikoerper, GB12654 antikoerper, dsim_GLEANR_9718 antikoerper, DsimGD25729 antikoerper, GD25729 antikoerper, EIF2C1 antikoerper, EIF2C antikoerper, GERP95 antikoerper, Q99 antikoerper, Eif2c1 antikoerper, ARGONAUTE 1 antikoerper, T1N15.2 antikoerper, T1N15_2 antikoerper, Argonaute-1 antikoerper, protein argonaute-2 antikoerper, argonaute 1 antikoerper, Argonaute 1 antikoerper, protein argonaute-1 antikoerper, argonaute 1, RISC catalytic component antikoerper, argonaute RISC catalytic subunit 1 antikoerper, Stabilizer of iron transporter SufD / Polynucleotidyl transferase antikoerper, AGO1 antikoerper, LOC552062 antikoerper, ago1 antikoerper, LOC659936 antikoerper, Dsim\AGO1 antikoerper, Ago1 antikoerper, LOC100386910 antikoerper, LOC100482671 antikoerper, LOC475337 antikoerper

Hintergrund:

Description: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).

Gene: AGO1

Molekulargewicht: 110 kDa

Gen-ID: 26523

UniProt: Q9UL18

Pathways: Fc-epsilon Rezeptor Signalübertragung, Regulatorische RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hormone Transport, Regulation of Actin Filament Polymerization, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization