AKR1C4 Antikörper

Produktnummer ABIN6259863

Produktdetails anti-AKR1C4 Antikörper

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: AKR1C4 Antibody detects endogenous levels of total AKR1C4

Kreuzreaktivität: Human, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AKR1C4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000 IHC 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu AKR1C4

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Andere Bezeichnung: AKR1C4 (AKR1C4 Produkte)

Synonyme: 3-alpha-HSD antikoerper, C11 antikoerper, CDR antikoerper, CHDR antikoerper, DD-4 antikoerper, DD4 antikoerper, HAKRA antikoerper, aldo-keto reductase family 1 member C4 antikoerper, AKR1C4 antikoerper

Hintergrund:

Description: Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.

Gene: AKR1C4

Molekulargewicht: 37 kDa

Gen-ID: 1109

UniProt: P17516

Pathways: Steroid Hormone Biosynthesis