ANG Antikörper (Internal Region)
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- Target Alle ANG Antikörper anzeigen
- ANG (Angiogenin (ANG))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ANG Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Spezifität
- Angiogenin Antibody detects endogenous levels of total Angiogenin.
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Angiogenin, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ANG Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- ANG (Angiogenin (ANG))
- Andere Bezeichnung
- ANG (ANG Produkte)
- Synonyme
- ALS9 antikoerper, HEL168 antikoerper, RNASE4 antikoerper, RNASE5 antikoerper, ANG antikoerper, AI385586 antikoerper, Ang1 antikoerper, Rnase5 antikoerper, Rnase5a antikoerper, ANG1 antikoerper, angiogenin antikoerper, angiogenin, ribonuclease, RNase A family, 5 antikoerper, ribonuclease A family member k6 antikoerper, ANG antikoerper, Ang antikoerper, RNASE6 antikoerper
- Hintergrund
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Description: Binds to actin on the surface of endothelial cells, once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.
Gene: ANG
- Molekulargewicht
- 17kDa
- Gen-ID
- 283
- UniProt
- P03950
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