Angiopoietin 2 Antikörper (N-Term)

Produktnummer ABIN6259925

Produktdetails anti-Angiopoietin 2 Antikörper

Target: Angiopoietin 2 (ANGPT2)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiopoietin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: Angiopoietin 2 Antibody detects endogenous levels of total Angiopoietin 2.

Homologie: Pig

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Angiopoietin 2, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Referenzen für anti-Angiopoietin 2 Antikörper (ABIN6259925)

Wu, Hu, Yin, Li, Zhang: "[Dose and timing of normal saline resuscitation on endothelial glycocalyx in early septic shock]." in: Zhonghua wei zhong bing ji jiu yi xue, Vol. 30, Issue 7, pp. 629-634, (2018) (PubMed).

Chen, Chen, Xu, Zhong, Zhang, Yang, Huang: "Electroacupuncture facilitates implantation by enhancing endometrial angiogenesis in a rat model of ovarian hyperstimulation." in: Biology of reproduction, (2018) (PubMed).

Details zu Angiopoietin 2

Target: Angiopoietin 2 (ANGPT2)

Andere Bezeichnung: ANGPT2 (ANGPT2 Produkte)

Synonyme: AGPT2 antikoerper, ANG2 antikoerper, Agpt2 antikoerper, Ang-2 antikoerper, Ang2 antikoerper, ang2 antikoerper, angpt2 antikoerper, ANGIOPOIETIN-2 antikoerper, ANG-2 antikoerper, ANGPT2 antikoerper, Angrp antikoerper, Rnase5b antikoerper, ANG3 antikoerper, C11orf2 antikoerper, C11orf3 antikoerper, FFR antikoerper, angiopoietin 2 antikoerper, angiopoietin 2b antikoerper, angiogenin, ribonuclease A family, member 2 antikoerper, VPS51, GARP complex subunit antikoerper, ANGPT2 antikoerper, Angpt2 antikoerper, angpt2b antikoerper, Ang2 antikoerper, VPS51 antikoerper

Hintergrund:

Description: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Gene: ANGPT2

Molekulargewicht: 57 kDa

Gen-ID: 285

UniProt: O15123

Pathways: RTK Signalweg