APOBR Antikörper (C-Term)

Produktnummer ABIN6259983

Produktdetails anti-APOBR Antikörper

Target: APOBR (Apolipoprotein B Receptor (APOBR))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOBR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: APOB48R Antibody detects endogenous levels of total APOB48R.

Homologie: Pig,Horse,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human APOB48R, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu APOBR

Target: APOBR (Apolipoprotein B Receptor (APOBR))

Andere Bezeichnung: APOBR (APOBR Produkte)

Synonyme: APOB48R antikoerper, Apob-48r antikoerper, Apob48r antikoerper, RGD1565169 antikoerper, APOB100R antikoerper, apolipoprotein B receptor antikoerper, apolipoprotein B48 receptor antikoerper, APOBR antikoerper, LOC745786 antikoerper, Apobr antikoerper

Hintergrund:

Description: Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.

Gene: APOBR

Molekulargewicht: 115 kDa

Gen-ID: 55911

UniProt: Q0VD83