APOBEC3A/B Antikörper

Produktnummer ABIN6259985

Produktdetails anti-APOBEC3A/B Antikörper

Target: APOBEC3A/B (APOBEC3A_B) (APOBEC3A and APOBEC3B Deletion Hybrid (APOBEC3A_B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOBEC3A/B Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Spezifität: APOBEC3A/B Antibody detects endogenous levels of total APOBEC3A/B

Kreuzreaktivität: Human

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human APOBEC3A/B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu APOBEC3A/B

Target: APOBEC3A/B (APOBEC3A_B) (APOBEC3A and APOBEC3B Deletion Hybrid (APOBEC3A_B))

Andere Bezeichnung: APOBEC3A/B (APOBEC3A_B Produkte)

Synonyme: A3A antikoerper, APOBEC3A and APOBEC3B deletion hybrid antikoerper, APOBEC3A_B antikoerper

Hintergrund:

Description: DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

Gene: APOBEC3A

Molekulargewicht: 23 kDa,46 kDa

Gen-ID: 100, 913, 187

UniProt: P31941, Q9UH17