PYDC1 Antikörper
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- Target Alle PYDC1 Antikörper anzeigen
- PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PYDC1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- ASC2 Antibody detects endogenous levels of total ASC2
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ASC2
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:1000-3000 IHC 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))
- Andere Bezeichnung
- ASC2 (PYDC1 Produkte)
- Synonyme
- ASC2 antikoerper, POP1 antikoerper, PYC1 antikoerper, pyrin domain containing 1 antikoerper, PYDC1 antikoerper
- Hintergrund
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Description: Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.
Gene: PYDC1
- Molekulargewicht
- 10 kDa
- Gen-ID
- 260434
- UniProt
- Q8WXC3
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