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ASPM Antikörper (Internal Region)

ASPM Reaktivität: Human, Ratte ELISA, IHC, IF, ICC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260082
  • Target Alle ASPM Antikörper anzeigen
    ASPM (Asp (Abnormal Spindle) Homolog, Microcephaly Associated (ASPM))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    Internal Region
    Reaktivität
    • 15
    • 1
    • 1
    Human, Ratte
    Wirt
    • 15
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ASPM Antikörper ist unkonjugiert
    Applikation
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blotting (WB)
    Spezifität
    ASPM Antibody detects endogenous levels of total ASPM.
    Homologie
    Bovine,Horse,Sheep,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ASPM, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product ASPM Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    ASPM (Asp (Abnormal Spindle) Homolog, Microcephaly Associated (ASPM))
    Andere Bezeichnung
    ASPM (ASPM Produkte)
    Synonyme
    Calmbp1 antikoerper, ASPM antikoerper, ASP antikoerper, MCPH5 antikoerper, D330028K02Rik antikoerper, Sha1 antikoerper, abnormal spindle microtubule assembly antikoerper, asp (abnormal spindle)-like, microcephaly associated (Drosophila) antikoerper, Aspm antikoerper, ASPM antikoerper, aspm antikoerper
    Hintergrund

    Description: Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seems to depend on the association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex (PubMed:28436967). May have a preferential role in regulating neurogenesis.

    Gene: ASPM

    Molekulargewicht
    410 kDa
    Gen-ID
    259266
    UniProt
    Q8IZT6
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