ATG4B Antikörper (Internal Region)
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- Target Alle ATG4B Antikörper anzeigen
- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ATG4B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- ATG4B Antibody detects endogenous levels of total ATG4B.
- Homologie
- Pig,Bovine,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ATG4B, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ATG4B Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
- Andere Bezeichnung
- ATG4B (ATG4B Produkte)
- Synonyme
- apg4b antikoerper, APG4B antikoerper, AUTL1 antikoerper, 2510009N07Rik antikoerper, AW048066 antikoerper, Apg4b antikoerper, Atg4bl antikoerper, Autl1 antikoerper, Aut2b2 antikoerper, autophagy related 4B cysteine peptidase antikoerper, autophagy-related 4b antikoerper, Peptidase family C54 protein antikoerper, cysteine protease ATG4B antikoerper, ATG4 autophagy related 4 homolog B (S. cerevisiae) antikoerper, autophagy related 4B, cysteine peptidase antikoerper, autophagy related 4B, cysteine peptidase L homeolog antikoerper, ATG4B antikoerper, Atg4b antikoerper, AT3G59950 antikoerper, Tsp_08582 antikoerper, Tsp_11599 antikoerper, atg4b antikoerper, atg4b.L antikoerper
- Hintergrund
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Description: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Gene: ATG4B
- Molekulargewicht
- 44kDa
- Gen-ID
- 23192
- UniProt
- Q9Y4P1
- Pathways
- Autophagie
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