BAK1 Antikörper (N-Term)
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- Target Alle BAK1 Antikörper anzeigen
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BAK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Bak Antibody detects endogenous levels of total Bak.
- Homologie
- Bovine,Horse,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Bak, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product BAK1 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- Andere Bezeichnung
- BAK1 (BAK1 Produkte)
- Synonyme
- BAK antikoerper, BAK-LIKE antikoerper, BCL2L7 antikoerper, CDN1 antikoerper, Bak antikoerper, N-BAK1 antikoerper, N-Bak antikoerper, Bak1 antikoerper, bak antikoerper, bak1 antikoerper, BCL2 antagonist/killer 1 antikoerper, BCL2-antagonist/killer 1 antikoerper, BCL2 antagonist/killer 1 L homeolog antikoerper, BAK1 antikoerper, Bak1 antikoerper, bak1.L antikoerper
- Hintergrund
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Description: Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases.
Gene: BAK1
- Molekulargewicht
- 25kDa
- Gen-ID
- 578
- UniProt
- Q16611
- Pathways
- Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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