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BAK1 Antikörper (N-Term)

BAK1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260195
  • Target Alle BAK1 Antikörper anzeigen
    BAK1 (BCL2-Antagonist/killer 1 (BAK1))
    Bindungsspezifität
    • 18
    • 16
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 81
    • 35
    • 26
    • 16
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 74
    • 5
    • 2
    • 1
    Kaninchen
    Klonalität
    • 67
    • 15
    Polyklonal
    Konjugat
    • 42
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BAK1 Antikörper ist unkonjugiert
    Applikation
    • 65
    • 26
    • 26
    • 18
    • 14
    • 13
    • 13
    • 10
    • 8
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Bak Antibody detects endogenous levels of total Bak.
    Homologie
    Bovine,Horse,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Bak, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product BAK1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    BAK1 (BCL2-Antagonist/killer 1 (BAK1))
    Andere Bezeichnung
    BAK1 (BAK1 Produkte)
    Synonyme
    BAK antikoerper, BAK-LIKE antikoerper, BCL2L7 antikoerper, CDN1 antikoerper, Bak antikoerper, N-BAK1 antikoerper, N-Bak antikoerper, Bak1 antikoerper, bak antikoerper, bak1 antikoerper, BCL2 antagonist/killer 1 antikoerper, BCL2-antagonist/killer 1 antikoerper, BCL2 antagonist/killer 1 L homeolog antikoerper, BAK1 antikoerper, Bak1 antikoerper, bak1.L antikoerper
    Hintergrund

    Description: Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases.

    Gene: BAK1

    Molekulargewicht
    25kDa
    Gen-ID
    578
    UniProt
    Q16611
    Pathways
    Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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