BCCIP Antikörper (C-Term)

Produktnummer ABIN6260217

Produktdetails anti-BCCIP Antikörper

Target: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCCIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: BCCIP Antibody detects endogenous levels of total BCCIP.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human BCCIP, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu BCCIP

Target: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Andere Bezeichnung: BCCIP (BCCIP Produkte)

Synonyme: zgc:110272 antikoerper, mp:zf637-1-000774 antikoerper, BCCIP antikoerper, DKFZp459K2416 antikoerper, MGC82792 antikoerper, tok-1 antikoerper, MGC89311 antikoerper, TOK-1 antikoerper, TOK1 antikoerper, 1110013J05Rik antikoerper, BRCA2 and CDKN1A interacting protein antikoerper, BRCA2 and CDKN1A interacting protein L homeolog antikoerper, BCCIP antikoerper, bccip antikoerper, bccip.L antikoerper, Bccip antikoerper

Hintergrund:

Description: During interphase, required for microtubule organizing and anchoring activities. During mitosis, required for the organization and stabilization of the spindle pole (PubMed:28394342). Isoform 2/alpha is particularly important for the regulation of microtubule anchoring, microtubule stability, spindle architecture and spindle orientation, compared to isoform 1/beta (PubMed:28394342). May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).

Gene: BCCIP

Molekulargewicht: 36 kDa

Gen-ID: 56647

UniProt: Q9P287