CACNA1E Antikörper (Internal Region)

Produktnummer ABIN6260395

Produktdetails anti-CACNA1E Antikörper

Target: CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: CACNA1E Antibody detects endogenous levels of total CACNA1E.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CACNA1E, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CACNA1E

Target: CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))

Andere Bezeichnung: CACNA1E (CACNA1E Produkte)

Synonyme: caV2.3 antikoerper, CACNA1E antikoerper, BII antikoerper, CACH6 antikoerper, CACNL1A6 antikoerper, Cav2.3 antikoerper, A430040I15 antikoerper, Cach6 antikoerper, Cacnl1a6 antikoerper, Cchra1 antikoerper, alpha1E antikoerper, CACHA1E antikoerper, calcium voltage-gated channel subunit alpha1 E antikoerper, calcium channel, voltage-dependent, R type, alpha 1E subunit antikoerper, CACNA1E antikoerper, cacna1e antikoerper, Cacna1e antikoerper

Hintergrund:

Description: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega-conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.

Gene: CACNA1E

Molekulargewicht: 262 kDa

Gen-ID: 777

UniProt: Q15878

Pathways: Carbohydrate Homeostasis