CaMK2 alpha/delta Antikörper
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- Target Alle CaMK2 alpha/delta Produkte
- CaMK2 alpha/delta
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CaMK2 alpha/delta Antikörper ist unkonjugiert
- Applikation
- Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Spezifität
- CaMK2 alpha/delta Antibody detects endogenous levels of total CaMK2 alpha/delta
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CaMK2 alpha/delta
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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Inhibition of Acid Sensing Ion Channel 3 Aggravates Seizures by Regulating NMDAR Function." in: Neurochemical research, (2018) (PubMed).
: "
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Inhibition of Acid Sensing Ion Channel 3 Aggravates Seizures by Regulating NMDAR Function." in: Neurochemical research, (2018) (PubMed).
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- Target
- CaMK2 alpha/delta
- Abstract
- CaMK2 alpha/delta Produkte
- Hintergrund
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Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).
Gene: CAMK2A
- Molekulargewicht
- 50kDa
- Gen-ID
- 815
- UniProt
- Q9UQM7, Q13557
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