CARD11 Antikörper (Internal Region)

Produktnummer ABIN6260459

Produktdetails anti-CARD11 Antikörper

Target: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: CARD11 Antibody detects endogenous levels of total CARD11.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CARD11, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CARD11

Target: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Andere Bezeichnung: CARD11 (CARD11 Produkte)

Synonyme: BENTA antikoerper, BIMP3 antikoerper, CARMA1 antikoerper, PPBL antikoerper, 0610008L17Rik antikoerper, 2410011D02Rik antikoerper, CARD11 antikoerper, LOC100232755 antikoerper, caspase recruitment domain family member 11 antikoerper, caspase recruitment domain family, member 11 antikoerper, caspase recruitment domain-containing protein 11 antikoerper, CARD11 antikoerper, Card11 antikoerper, LOC100550812 antikoerper, card11 antikoerper

Hintergrund:

Description: Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. Also activates the TORC1 signaling pathway.

Gene: CARD11

Molekulargewicht: 133 kDa

Gen-ID: 84433

UniProt: Q9BXL7

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, BCR Signaling