Caspase 3 Antikörper (N-Term)
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- Target Alle Caspase 3 (CASP3) Antikörper anzeigen
- Caspase 3 (CASP3)
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caspase 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Caspase 3 Antibody detects endogenous levels of total Caspase 3.
- Homologie
- Pig,Bovine,Horse,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Caspase 3, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CASP3 Primärantikörper
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anti-Caspase 3 (CASP3) (AA 60-100) antibody
CASP3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege WB, IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 67-175) antibodyCASP3 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 220-236), (C-Term) antibodyCASP3 Reaktivität: Human WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) antibodyCASP3 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Maus Monoclonal 5E1 unconjugated
anti-Caspase 3 (CASP3) (pSer150) antibodyCASP3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (Internal Region) antibodyCASP3 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 100-200) antibodyCASP3 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (cleaved) antibodyCASP3 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 29-175) antibodyCASP3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 29-175) antibodyCASP3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C3 unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Caspase 3 (CASP3)
- Andere Bezeichnung
- CASP3 (CASP3 Produkte)
- Hintergrund
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Description: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Gene: CASP3
- Molekulargewicht
- 32kDa
- Gen-ID
- 836
- UniProt
- P42574
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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