Caspase 1 Antikörper (C-Term)
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- Target Alle Caspase 1 (CASP1) Antikörper anzeigen
- Caspase 1 (CASP1)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caspase 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Caspase 1 Antibody detects endogenous levels of total Caspase 1.
- Homologie
- Pig,Bovine,Rabbit
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Caspase 1, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CASP1 Primärantikörper
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anti-Caspase 1 (CASP1) (AA 317-404) antibody
CASP1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-297) antibodyCASP1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 119-296) antibodyCASP1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-297) antibodyCASP1 Reaktivität: Schwein WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 1-311) antibodyCASP1 Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 1-100) antibodyCASP1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 3D2 unconjugated
anti-Caspase 1 (CASP1) (AA 135-152), (N-Term) antibodyCASP1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-269) antibodyCASP1 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-269) antibodyCASP1 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) antibodyCASP1 Reaktivität: Human WB, IHC (p), IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Caspase 1 (CASP1)
- Andere Bezeichnung
- CASP1 (CASP1 Produkte)
- Hintergrund
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Description: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive (PubMed:28314590).
Gene: CASP1
- Molekulargewicht
- 45 kDa 20kDa
- Gen-ID
- 834
- UniProt
- P29466
- Pathways
- Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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