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CBP Antikörper (C-Term)

CREBBP Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260516
  • Target Alle CBP (CREBBP) Antikörper anzeigen
    CBP (CREBBP) (CREB Binding Protein (CREBBP))
    Bindungsspezifität
    • 11
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 85
    • 41
    • 36
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 81
    • 7
    Kaninchen
    Klonalität
    • 81
    • 7
    Polyklonal
    Konjugat
    • 42
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CBP Antikörper ist unkonjugiert
    Applikation
    • 66
    • 44
    • 22
    • 19
    • 12
    • 12
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    CREB-BP Antibody detects endogenous levels of total CREB-BP.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CREB-BP, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product CREBBP Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    CBP (CREBBP) (CREB Binding Protein (CREBBP))
    Andere Bezeichnung
    CREBBP (CREBBP Produkte)
    Synonyme
    CBP antikoerper, KAT3A antikoerper, RSTS antikoerper, AW558298 antikoerper, CBP/p300 antikoerper, p300/CBP antikoerper, RTS antikoerper, cbp antikoerper, crebbp antikoerper, kat3a antikoerper, rsts antikoerper, hmm291030 antikoerper, Nejire antikoerper, CREB binding protein antikoerper, CREB binding protein L homeolog antikoerper, histone acetyltransferase p300 antikoerper, CREBBP antikoerper, Crebbp antikoerper, crebbp.L antikoerper, LOC100123220 antikoerper
    Hintergrund

    Description: Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA, acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902).

    Gene: CREBBP

    Molekulargewicht
    265kDa
    Gen-ID
    1387
    UniProt
    Q92793
    Pathways
    T-Zell Rezeptor Signalweg, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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