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CBX5 Antikörper (Internal Region)

CBX5 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260520
  • Target Alle CBX5 Antikörper anzeigen
    CBX5 (Chromobox Homolog 5 (CBX5))
    Bindungsspezifität
    • 15
    • 15
    • 12
    • 10
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 107
    • 42
    • 27
    • 15
    • 8
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 107
    • 18
    • 2
    • 2
    Kaninchen
    Klonalität
    • 97
    • 31
    • 1
    Polyklonal
    Konjugat
    • 66
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser CBX5 Antikörper ist unkonjugiert
    Applikation
    • 80
    • 46
    • 28
    • 28
    • 24
    • 21
    • 17
    • 9
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    HP1 alpha Antibody detects endogenous levels of total HP1 alpha.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human HP1 alpha, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product CBX5 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    CBX5 (Chromobox Homolog 5 (CBX5))
    Andere Bezeichnung
    CBX5 (CBX5 Produkte)
    Hintergrund

    Description: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

    Gene: CBX5

    Molekulargewicht
    22kDa
    Gen-ID
    23468
    UniProt
    P45973
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