CBX5 Antikörper (Internal Region)

Produktnummer ABIN6260520

Produktdetails anti-CBX5 Antikörper

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: HP1 alpha Antibody detects endogenous levels of total HP1 alpha.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HP1 alpha, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CBX5

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Andere Bezeichnung: CBX5 (CBX5 Produkte)

Synonyme: HP1 antikoerper, HP1A antikoerper, id:ibd2026 antikoerper, wu:fc63e02 antikoerper, wu:fe47g12 antikoerper, wu:fi03h05 antikoerper, zgc:158601 antikoerper, CBX5 antikoerper, cbx5 antikoerper, MGC64354 antikoerper, 2610029O15Rik antikoerper, C75991 antikoerper, Hp1a antikoerper, Hp1alpha antikoerper, chromobox 5 antikoerper, chromobox homolog 5 (HP1 alpha homolog, Drosophila) antikoerper, chromobox 5 S homeolog antikoerper, CBX5 antikoerper, cbx5 antikoerper, Cbx5 antikoerper, cbx5.S antikoerper

Hintergrund:

Description: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Gene: CBX5

Molekulargewicht: 22kDa

Gen-ID: 23468

UniProt: P45973