CBX6 Antikörper (N-Term)
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- Target Alle CBX6 Antikörper anzeigen
- CBX6 (Chromobox Homolog 6 (CBX6))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CBX6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- CBX6 Antibody detects endogenous levels of total CBX6.
- Homologie
- Pig,Bovine,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CBX6, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- CBX6 (Chromobox Homolog 6 (CBX6))
- Andere Bezeichnung
- CBX6 (CBX6 Produkte)
- Synonyme
- cbx6 antikoerper, CBX6 antikoerper, zgc:101049 antikoerper, chromobox 6 antikoerper, chromobox 6 L homeolog antikoerper, chromobox homolog 6a antikoerper, cbx6 antikoerper, CBX6 antikoerper, Cbx6 antikoerper, cbx6.L antikoerper, cbx6a antikoerper
- Hintergrund
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Description: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity). May have a PRC1-independent function in embryonic stem cells (By similarity).
Gene: CBX6
- Molekulargewicht
- 44kDa
- Gen-ID
- 23466
- UniProt
- O95503
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