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CCDC99 Antikörper (C-Term)

CCDC99 Reaktivität: Human, Maus ELISA, WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260531
  • Target Alle CCDC99 Antikörper anzeigen
    CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))
    Bindungsspezifität
    • 15
    • 9
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 28
    • 16
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 41
    • 3
    Kaninchen
    Klonalität
    • 42
    • 2
    Polyklonal
    Konjugat
    • 14
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCDC99 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 17
    • 13
    • 13
    • 7
    • 4
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    CCDC99 Antibody detects endogenous levels of total CCDC99.
    Homologie
    Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CCDC99, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product CCDC99 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))
    Andere Bezeichnung
    SPDL1 (CCDC99 Produkte)
    Synonyme
    CCDC99 antikoerper, CG15415 antikoerper, Dmel\\CG15415 antikoerper, SPINDLY antikoerper, ccdc99 antikoerper, 1700018I02Rik antikoerper, 2600001J17Rik antikoerper, 2810049B11Rik antikoerper, AA409762 antikoerper, Ccdc99 antikoerper, RGD1306908 antikoerper, ccdc99-a antikoerper, ccdc99-b antikoerper, spdl1-a antikoerper, spdl1-b antikoerper, spdl1 antikoerper, spindle apparatus coiled-coil protein 1 antikoerper, CG15415 gene product from transcript CG15415-RB antikoerper, Tetratricopeptide repeat (TPR)-like superfamily protein antikoerper, spindle apparatus coiled-coil protein 1 L homeolog antikoerper, spindle apparatus coiled-coil protein 1 S homeolog antikoerper, SPDL1 antikoerper, Spindly antikoerper, SPY antikoerper, spdl1 antikoerper, Spdl1 antikoerper, spdl1.L antikoerper, spdl1.S antikoerper
    Hintergrund

    Description: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment (PubMed:17576797, PubMed:19468067). Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).

    Gene: SPDL1

    Molekulargewicht
    70kDa
    Gen-ID
    54908
    UniProt
    Q96EA4
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